MTHFR is one genetic susceptibility to vaccine injury, but it’s not the only one. There are several others.
Human Leukocyte Antigens
“The HLA gene family provides instructions for making a group of related proteins known as the human leukocyte antigen (HLA) complex. The HLA complex helps the immune system distinguish the body’s own proteins from proteins made by foreign invaders such as viruses and bacteria.”
“More than 100 diseases have been associated with different alleles of HLA genes.”
Acquired autoimmunity after viral vaccination is caused by molecular mimicry and antigen complimentarity in the presence of an immunologic adjuvant and specific HLA patterns.
Autoimmune/auto-inflammatory syndrome induced by adjuvants (ASIA) after quadrivalent human papillomavirus vaccination in Colombians: a call for personalised medicine.
“This was a case study in which 3 patients with autoimmune/auto-inflammatory syndrome induced by adjuvants (ASIA) after quadrivalent human papillomavirus vaccination (HPV) were evaluated and described. All the patients were women. Diagnosis consisted of HLA-B27 enthesitis related arthritis, rheumatoid arthritis and systemic lupus erythematous, respectively. Our results highlight the risk of developing ASIA after HPV vaccination and may serve to increase the awareness of such a complication. Factors that are predictive of developing autoimmune diseases should be examined at the population level in order to establish preventive measures in at-risk individuals for whom healthcare should be personalized and participatory.”
🛑 Autoimmune/Inflammatory Syndrome Induced by Adjuvants and Thyroid Autoimmunity.
Bivalent HPV vaccine safety depending on subtypes of juvenile idiopathic arthritis.
Chronic anterior uveitis following bacille Calmette-Guérin vaccination: molecular mimicry in action?
HLA haplotype in a patient with systemic lupus erythematosus triggered by hepatitis B vaccine.
Subacute thyroiditis and dyserythropoesis after influenza vaccination suggesting immune dysregulation.
Variability in Humoral Immunity to Measles Vaccine: New Developments.
“Despite the existence of an effective measles vaccine, resurgence in measles cases in the USA and across Europe has occurred, including in individuals vaccinated with two doses of the vaccine.”
HLA, but not vaccine related
Fibromyalgia in 300 adult index patients with primary immunodeficiency.
(Note, keywords – Fibromyalgia, Interstitial cystitis, CFS, HLA, Sjogrens, HLA = human leukocyte antigen genotype)
“CONCLUSIONS: Fibromyalgia is common in non-Hispanic white adult index patients with primary immunodeficiency, especially women. Chronic fatigue, Sjögren’s syndrome, and IC are significantly associated with fibromyalgia after adjustment for other independent variables.”
“…HLA-A*29, B*44 positivity were greater in patients with fibromyalgia.”