Hepatitis B

Acute Disseminated Encephalomyelitis following Vaccination against Hepatitis B in a Child: A Case Report and Literature Review

“Acute disseminated encephalomyelitis (ADEM) is an inflammatory demyelinating disease of the central nervous system, which has been associated with several vaccines such as rabies, diphtheria-tetanus-polio, smallpox, measles, mumps, rubella, Japanese B encephalitis, pertussis, influenza, and the Hog vaccine. Here, we presented a case of 12-year-old child who suffered from ADEM three weeks after hepatitis B vaccination. He was admitted to our hospital with symptoms of weakness of limbs, high fever, and alteration of consciousness. Some abnormalities were also found in CSF. Treatment with high-dose corticosteroids and intravenous immunoglobulin had significant effect, with marked improvement of the clinical symptoms and the results of CSF. The findings of MRI also detected some abnormal lesions located in both brain and spinal cord. The clinical features, the findings of CSF and MRI, and therapeutic effect may contribute to such diagnosis of ADEM.”

#ADEM #Neurological #Encephalomyelitis #Hepatitis B #Vaccine #MedScienceResearch

https://www.hindawi.com/journals/crinm/2016/2401809/

[Acute transverse myelitis secondary to hepatitis B vaccination].

#Transverse #Myelitis #Autoimmunity #Hepatitis B #Vaccine #Neurological #MedScienceResearch

https://www.ncbi.nlm.nih.gov/m/pubmed/11027094/

🛑 Adverse events associated with childhood vaccines other than pertussis and rubella. Summary of a report from the Institute of Medicine. 

The committee found that the evidence favored acceptance of a causal relation between diphtheria and tetanus toxoids and Guillain-Barré syndrome and brachial neuritis, between measles vaccine and anaphylaxis, between oral polio vaccine and Guillain-Barré syndrome, and between unconjugated Hib vaccine and susceptibility to Hib disease. The committee found that the evidence established causality between diphtheria and tetanus toxoids and anaphylaxis, between measles vaccine and death from measles vaccine-strain viral infection, between measles-mumps-rubella vaccine and thrombocytopenia and anaphylaxis, between oral polio vaccine and poliomyelitis and death from polio vaccine-strain viral infection, and between hepatitis B vaccine and anaphylaxis.

#Death #Guillain #Barre #Polio #Anaphylaxis #Hib #Failure #Tetanus #MMR #Measles #Poliomyelitis #Hepatitis B #Thrombocytopenia
#Vaccine #MedScienceResearch

https://www.ncbi.nlm.nih.gov/m/pubmed/8182813/

Anetoderma occurring after hepatitis B vaccination.

“Anetoderma is an elastolytic disorder of unknown origin. To our knowledge, anetoderma secondary to hepatitis B immunization has been described only once in the literature, in two siblings vaccinated at the same time. We describe, what we believe to be an additional case of such a rare disorder in a 21-year-old man. He presented with white spots and papules on his neck, upper limbs and trunk, that had developed gradually within the last 6 years without any symptoms. The initial lesions were red macules, which gradually enlarged in size and number, becoming pale. Biopsy of a sack-like lesion revealed normal epidermis and a discrete mononuclear infiltrate throughout the dermis. Association of anetoderma with hepatitis B vaccination is speculated here, as suggested by history of vaccination two weeks prior to the onset of skin eruption and ruling out other possible causes of anetoderma.”

#Dermatological #Hepatitis B #Anetoderma #Vaccine #MedScienceResearch

https://www.ncbi.nlm.nih.gov/m/pubmed/16880577/

Autoimmune hazards of hepatitis B vaccine.

#Autoimmunity #Hepatitis B #Molecular #Mimicry
#Vaccine #MedScienceResearch

https://www.ncbi.nlm.nih.gov/m/pubmed/15722255/

Bell’s palsy as a possible complication of hepatitis B vaccination in a child.

#Bells #Palsy #Hepatitis B #Neurological #Vaccine #MedScienceResearch

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2928079/

Chronic fatigue syndrome and fibromyalgia following immunization with the hepatitis B vaccine: another angle of the ‘autoimmune (auto-inflammatory) syndrome induced by adjuvants’ (ASIA).

#Chronic #Fatigue #Syndrome
#Fibromyalgia #Autoimmunity #Hepatitis B #ASIA #Vaccine #MedScienceResearch

https://www.ncbi.nlm.nih.gov/m/pubmed/25427994/

Chronic fatigue syndrome with autoantibodies–the result of an augmented adjuvant effect of hepatitis-B vaccine and silicone implant.

#Fibromyalgia #Autoimmunity
#Chronic #Fatigue #Syndrome #Gulf #War #Syndrome #Hepatitis B #Vaccine #Macrophagic #Myofasciitis #MedScienceResearch

https://www.ncbi.nlm.nih.gov/m/pubmed/18725327/

The development of rheumatoid arthritis after recombinant hepatitis B vaccination.

#Rheumatoid #Arthritis #Hepatitis B #Autoimmunity #Vaccine #MedScienceResearch

https://www.ncbi.nlm.nih.gov/m/pubmed/9733447/

Evolution of multiple sclerosis in France since the beginning of hepatitis B vaccination

#Multiple #Sclerosis #Hepatitis B
#Vaccine #MedScienceResearch

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4266455/

Guillain-Barré syndrome after vaccination in United States: data from the Centers for Disease Control and Prevention/Food and Drug Administration Vaccine Adverse Event Reporting System (1990-2005).

“There were 1000 cases (mean age, 47 years) of GBS reported after vaccination in the United States between 1990 and 2005. The onset of GBS was within 6 weeks in 774 cases, >6 weeks in 101, and unknown in 125. Death and disability after the event occurred in 32 (3.2%) and 167 (16.7%) subjects, respectively. The highest number (n = 632) of GBS cases was observed in subjects receiving influenza vaccine followed by hepatitis B vaccine (n = 94). Other vaccines or combinations of vaccines were associated with 274 cases of GBS. The incidence of GBS after influenza vaccination was marginally higher in subjects <65 years compared with those >or=65 years (P = 0.09); for hepatitis vaccine, the incidence was significantly higher (P < 0.0001) in the <65 group. Death was more frequent in subjects >or=65 years compared with those <65 years (P < 0.0001)." #Guillain #Barre #Death #Neurological #Influenza #Hepatitis B #Flu #Vaccine #MedScienceResearch https://www.ncbi.nlm.nih.gov/m/pubmed/19730016/

Guillain – Barre’ syndrome following recombinant hepatitis B vaccine and literature review.

“A 17 year-old woman developed progressive quadriparesis with bilateral facial diplegia after immunization with recombinant hepatitis B vaccine 3 days prior. Cerebrospinal fluid analysis revealed acellular fluid with high protein level. The electrodiagnosis was compatible with demyelinating polyneuropathy. Other potential causes of Guillain-Barre’ syndrome (GBS) were ruled out. Her motor power gradually improved and returned to normal later. The temporal relationship between GBS and vaccination was suggestive of a vaccine-induced cause. Mechanisms of this very rare complication are proposed with a literature review.”

#Paralysis #Vaccine #Neurological #Hepatitis B #Guillain #Barre #MedScienceResearch

https://www.ncbi.nlm.nih.gov/m/pubmed/11075984/

Hair loss after routine immunizations.

“A total of 60 evaluable reports submitted since 1984 and coded for “alopecia” after immunizations included 16 with positive rechallenge (hair loss after vaccination on more than 1 occasion), 4 of which were definite and 12 possible or probable. Of the 60 cases, 46 had received hepatitis B vaccines. Both of the currently available recombinant products, as well as the former plasma-derived product, were represented. Females predominated in all age groups. The majority of patients recovered, but clinical features, such as intervals from vaccination until onset and the extent and reversibility of hair loss, varied widely. Nine patients reported previous medication allergy.”

#Hair #Loss #Alopecia #Hepatitis B #Vaccine #MedScienceResearch

https://www.ncbi.nlm.nih.gov/m/pubmed/9326478/

Hepatitis B vaccination and adult associated gastrointestinal reactions: a follow-up analysis.

#Hepatitis B #Gastrointestinal #Liver #Vaccine  #MedScienceResearch

https://www.ncbi.nlm.nih.gov/m/pubmed/12397738/

🛑 Hepatitis B vaccination and associated oral manifestations: a non-systematic review of literature and case reports.

“After reviewing the literature, we observed that complications seen after Hepatitis B vaccination are sudden infant death syndrome, multiple sclerosis, chronic fatigue syndrome, idiopathic thrombocytopenic purpura, vasculititis optic neuritis, anaphylaxis, systemic lupus erytymatosus, lichen planus and neuro-muscular disorder.”

#Sudden #Infant #Death #Syndrome #SIDS #Hepatitis B #Multiple #Sclerosis #Neurological #Chronic #Fatigue #Syndrome #Lupus #Dermatological #Anaphylaxis #Ophthalmological #Thrombocytopenia
#Vaccine #MedScienceResearch

https://www.ncbi.nlm.nih.gov/m/pubmed/25506472/

Hepatitis B vaccination of male neonates and autism diagnosis

#Autism #Hepatitis B #Vaccine #MedScienceResearch

https://www.ncbi.nlm.nih.gov/m/pubmed/21058170/

Hepatitis B vaccine induces apoptotic death in Hepa1-6 cells.

#Hepatitis B #Vaccine #Mitochondria #Apoptosis #MedScienceResearch

https://www.ncbi.nlm.nih.gov/m/pubmed/22249285/

🛑 Hepatitis B Vaccines—to Switch or Not to Switch

“Shortly after the licensure of Heptavax-B in 1981 and its general availability in July 1982, the discovery of the acquired immunodeficiency syndrome (AIDS) among male homosexuals threatened the success of this product, since some of the hepatitis B surface antigen (HBsAg)-positive plasma donors were members of this high-risk group. Intensive epidemiologic, virological, and serological evaluations were launched, which eventually found no evidence for the transmission of AIDS to recipients of the plasma-derived HBsAg vaccine.”

#AIDS #HIV #Hepatitis B #Contamination #Vaccine
#MedScienceResearch

http://jamanetwork.com/journals/jama/article-abstract/366144

Hepatitis vaccine pluses outweigh threat of AIDS.

Fraser B. Dent Stud. 1983.

No abstract available
PMID 6583121

#AIDS #HIV #Hepatitis B #Contamination #Vaccine
#MedScienceResearch

https://www.ncbi.nlm.nih.gov/m/pubmed/6583121/

HLA haplotype in a patient with systemic lupus erythematosus triggered by hepatitis B vaccine.

#Lupus #Autoimmunity #Hepatitis B #Molecular #Mimicry #HLA #Vaccine #MedScienceResearch

https://www.ncbi.nlm.nih.gov/m/pubmed/20630136

🛑 Hypotonic-hyporesponsive episode in a 7-month-old infant after receipt of multiple vaccinations.

“A 7-month-old boy became difficult to arouse, was limp and had blue extremities 8 hours after immunization with intravenous poliovirus, diphtheria-tetanus toxoids-acellular pertussis, Haemophilus influenzae type b-hepatitis B virus and pneumococcal vaccines. The hypotonic-hyporesponsive episode had resolved by the time the infant was seen in an emergency department 1 hour later. The report describes hypotonic-hyporesponsive episode, encourages reporting of vaccine-associated adverse events and discusses prognosis and implications for subsequent immunization.”

#Hypotonic #Hyporesponsive #HHE #Polio #DTaP #Hib #Hepatitis B #Pneumococcal
#Vaccine #MedScienceResearch

https://www.ncbi.nlm.nih.gov/m/pubmed/16282941/

Kawasaki disease in an infant following immunisation with hepatitis B vaccine.

“The known association between hepatitis B and vasculitis has been reported in rare cases in adults after hepatitis B vaccination. We here describe a 35-day-old infant who developed Kawasaki disease 1 day after receiving his second dose of hepatitis B vaccine. Although extremely rare, this possible side effect should be noted and further investigated.”

#Kawasaki #Hepatitis B #Vasculitis #Vaccine #MedScienceResearch

https://www.ncbi.nlm.nih.gov/m/pubmed/14677029/

Lumbosacral acute demyelinating polyneuropathy following hepatitis B vaccination.

“We report a patient who presented with an acute inflammatory demyelinating polyneuropathy, that followed the second injection of a hepatitis B vaccination, and characterized by motor and sensory deficit restricted to lower limbs and perineum, and persistent bladder dysfunction. The relationship between the preceding event and neurological disease is discussed.”

#Neurological #Hepatitis B #Bladder #Vaccine #MedScienceResearch

https://www.ncbi.nlm.nih.gov/m/pubmed/10520897/

Macrophagic myofasciitis lesions assess long-term persistence of vaccine-derived aluminium hydroxide in muscle.

#Aluminum #Macrophagic #Myofasciitis #Hepatitis A #Musculoskeletal #Hepatitis B #Tetanus #Vaccine #MedScienceResearch

https://www.ncbi.nlm.nih.gov/m/pubmed/11522584/

Mental nerve neuropathy as a result of hepatitis B vaccination.

#Neurological #Hepatitis B #Vaccine #MedScienceResearch

https://www.ncbi.nlm.nih.gov/m/pubmed/9195619/

Multiple evanescent white dot syndrome after hepatitis B vaccine.

#Ophthalmological #Eyes #Hepatitis#Vaccine #MedScienceResearch

https://www.ncbi.nlm.nih.gov/m/pubmed/8794720/

Multiple sclerosis and hepatitis B vaccination: could minute contamination of the vaccine by partial hepatitis B virus polymerase play a role through molecular mimicry?

“Reports of multiple sclerosis developing after hepatitis B vaccination have led to the concern that this vaccine might be a cause of multiple sclerosis in previously healthy subjects. Some articles evidenced that minor Hepatitis B virus (HBV) polymerase proteins could be produced by alternative transcriptional or translational strategies. Their detection is very difficult because they are in minute concentration and probably enzymatically inactive, however, it was shown that they could be exposed on the outside of the virus particles and also be immunogenic. In addition, HBV polymerase shares significant amino acid similarities with the human myelin basic protein. We hypothesise that some of the apparent adverse reactions to the vaccine could be due to a process called of molecular mimicry, the HBV polymerase, which could be a contaminant in the recombinant or plasma-derived vaccines, could act as autoantigens and induce autoimmune demyelinating diseases such as multiple sclerosis.”

#Multiple #Sclerosis #Hepatitis B
#Autoimmunity #Molecular #Mimicry #Contamination #MedScienceResearch

https://www.ncbi.nlm.nih.gov/m/pubmed/15908138/

🛑 Neonatal deaths after hepatitis B vaccine: the vaccine adverse event reporting system, 1991-1998.

“RESULTS: Of 1771 neonatal reports, there were 18 deaths in 8 boys and 9 girls (1 patient unclassified). The mean age at vaccination for these 18 cases was 12 days (range, 1-27 days); median time from vaccination to onset of symptoms was 2 days (range, 0-20 days); and median time from symptoms to death was 0 days (range, 0-15 days). The mean birth weight of the neonates (n = 15) was 3034 g (range, 1828-4678 g). The causes of death for the 17 autopsied cases were sudden infant death syndrome for 12, infection for 3, and 1 case each of intracerebral hemorrhage, accidental suffocation, and congenital heart disease.”

#Sudden #Infant #Death #Syndrome #SIDS #Hepatitis B
#Vaccine #MedScienceResearch

https://www.ncbi.nlm.nih.gov/m/pubmed/10591306/

Neuritis of the optic nerve after vaccinations against hepatitis A, hepatitis B and yellow fever

#Eyes #Ophthalmological
#Yellow #Fever #Hepatitis A #Hepatitis B #Vaccine #MedScienceResearch

https://www.ncbi.nlm.nih.gov/m/pubmed/11706386/

A one year followup of chronic arthritis following rubella and hepatitis B vaccination based upon analysis of the Vaccine Adverse Events Reporting System (VAERS) database.

#Arthritis #Hepatitis B #Rubella #Vaccine #Autoimmunity #MedScienceResearch

https://www.ncbi.nlm.nih.gov/m/pubmed/12508767/

Optic neuritis following hepatitis B vaccination in a 9-year-old girl.

“A majority of the ophthalmological complications seen following hepatitis B vaccination consist of vision loss, optic neuritis, papillary edema, uveitis, acute placoid pigment epitheliopathy and central vein occlusion. We present a 9-year-old girl who was referred to our hospital with decrease in vision and pain in the left eye a week after hepatitis B vaccination.”

#Ophthalmological #Hepatitis B #Eyes #Vaccine #MedScienceResearch

https://www.ncbi.nlm.nih.gov/m/pubmed/19948437/

Post-vaccination encephalomyelitis: literature review and illustrative case.

#ADEM  #Neurological
#Encephalomyelitis #Rabies #Tetanus #Polio #Smallpox #MMR #DTP #Influenza #Hepatitis B #Vaccine #MedScienceResearch

https://www.ncbi.nlm.nih.gov/m/pubmed/18976924/

Recombinant hepatitis B vaccine and the risk of multiple sclerosis: a prospective study.

#Hepatitis B #Autoimmunity #MS #Multiple #Sclerosis #Vaccine #MedScienceResearch

https://www.ncbi.nlm.nih.gov/m/pubmed/15365133/

Recombinant Human Hepatitis B Vaccine Initiating Alopecia Areata: Testing the Hypothesis Using the C3H/HeJ Mouse Model

#Alopecia #Hair #Hepatitis B #Vaccine #MedScienceResearch

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2956183/

Seronegative Neuromyelitis Optica Spectrum Disorder following Exposure to Hepatitis B
Vaccination.

#Ophthalmological #Neurological #Eyes #Hepatitis B #Vaccine #MedScienceResearch

https://www.ncbi.nlm.nih.gov/m/pubmed/25969683

Severe necrotizing pancreatitis following combined hepatitis A and B vaccination.

#Pancreatitis #Hepatitis A #Hepatitis B #Vaccine #MedScienceResearch

https://www.ncbi.nlm.nih.gov/m/pubmed/17261831/

Simultaneous sudden infant death syndrome.

#SIDS #Polio #DTP #Hepatitis B #MedScienceResearch
#Vaccine

https://www.ncbi.nlm.nih.gov/pubmed/17654772

Sjögren’s syndrome occurring after hepatitis B vaccination.

#Sjogrens #Hepatitis B #Vaccine #MedScienceResearch

https://www.ncbi.nlm.nih.gov/m/pubmed/11014366/

Status epilepticus and lymphocytic pneumonitis following hepatitis B vaccination.

“The case reported refers to a patient who developed status epilepticus in the day of her third dose of hepatitis B vaccination and we review the literature on this subject. A 12 year-old girl, without a relevant previous history, taking no drugs, developed a seizure attack followed by unconsciousness, and eventually died after three days of her third dose of hepatitis B (HB) vaccination. Autopsy study revealed cerebral edema with congestion and herniation and diffuse interstitial type pneumonitis. There seem to be a straight forward time relationship between the third HB vaccine, the event of convulsion and the sudden death of the patient. We suggest that, in some cases, vaccination may be the triggering factor for autoimmune and neurological disturbances in genetically predisposed individuals and physicians should be aware of this possible association.”

#Death #Neurological #Seizures #Autoimmunity #Hepatitis B #Vaccine #MedScienceResearch

https://www.ncbi.nlm.nih.gov/m/pubmed/18549949/

Temporal Association of Certain Neuropsychiatric Disorders Following Vaccination of Children and Adolescents: A Pilot Case-Control Study.

#Anxiety #ADHD #Attention #Deficit #Disorder #Tics #OCD #Anorexia
#Obsessive #Compulsive #Disorder
#Psychiatric #Meningitis
#Hepatitis A #Hepatitis B
#Autoimmunity #Influenza #Flu #Neurological

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5244035/

Ten cases of systemic lupus erythematosus related to hepatitis B vaccine.

#Lupus #Hepatitis B #Hepatitis #Vaccine #MedScienceResearch

https://www.ncbi.nlm.nih.gov/m/pubmed/19880567/

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Thimerosal exposure and disturbance of emotions specific to childhood and adolescence: A case-control study in the Vaccine Safety Datalink (VSD) database. 2017

#Psychiatric #Thimerosal #Mercury #Hepatitis B #Vaccine #MedScienceResearch

https://www.ncbi.nlm.nih.gov/m/pubmed/28102704

Thimerosal-containing Hepatitis B Vaccine Exposure is Highly Associated with Childhood Obesity: A Case-control Study Using the Vaccine Safety Datalink.

#Obesity #Thimerosal #Hepatitis B #Vaccine #MedScienceResearch

https://www.ncbi.nlm.nih.gov/m/pubmed/27583238/

Transient facial nerve paralysis (Bell’s palsy) following administration of hepatitis B recombinant vaccine: a case report.

#Bells #Palsy #Hepatitis B #Neurological #Vaccine #MedScienceResearch

https://www.ncbi.nlm.nih.gov/m/pubmed/24457866/

Transverse myelitis and vaccines: a multi-analysis.

“We have disclosed 37 reported cases of transverse myelitis associated with different vaccines including those against hepatitis B virus, measles-mumps-rubella, diphtheria-tetanus-pertussis and others, given to infants, children and adults.”

#Transverse #Myelitis #Autoimmunity  #Neurological #Immune #Hepatitis B #MMR #DTP #Vaccine #MedScienceResearch

https://www.ncbi.nlm.nih.gov/m/pubmed/19880568

Mar, 06, 2017

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