Arthritis

Scientific studies and articles from PubMed on vaccines and arthritis:

Adjuvants- and vaccines-induced autoimmunity: animal models.

“In some cases, adjuvants may trigger generalized autoimmune response, resulting in multiple auto-antibodies, but sometimes they can reproduce human autoimmune diseases including rheumatoid arthritis, systemic lupus erythematosus, Sjögren syndrome, autoimmune thyroiditis and antiphospholipid syndrome and may provide insights about the potential adverse effects of adjuvants.”

#Thyroid #Arthritis #Lupus #Sjogren #Autoimmunity #Antiphospholipid #Animals #Veterinary #Musculoskeletal #Neurological #Vaccine
#MedScienceResearch

https://www.ncbi.nlm.nih.gov/m/pubmed/27417999

Autoimmune/auto-inflammatory syndrome induced by adjuvants (ASIA) after quadrivalent human papillomavirus vaccination in Colombians: a call for personalised medicine.

“This was a case study in which 3 patients with autoimmune/auto-inflammatory syndrome induced by adjuvants (ASIA) after quadrivalent human papillomavirus vaccination (HPV) were evaluated and described. All the patients were women. Diagnosis consisted of HLA-B27 enthesitis related arthritis, rheumatoid arthritis and systemic lupus erythematous, respectively. Our results highlight the risk of developing ASIA after HPV vaccination and may serve to increase the awareness of such a complication. Factors that are predictive of developing autoimmune diseases should be examined at the population level in order to establish preventive measures in at-risk individuals for whom healthcare should be personalized and participatory.”

#Gardasil #ASIA #Autoimmunity #HLA #Arthritis #Lupus #Vaccine #MedScienceResearch

https://www.ncbi.nlm.nih.gov/m/pubmed/25962455/

🛑 Autoimmune/Inflammatory Syndrome Induced by Adjuvants and Thyroid Autoimmunity.

#Thyroid #Autoimmunity #ASIA #HLA #Lupus #Arthritis #Hashimotos #Vaccine #MedScienceResearch

Full article:

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5256113/

https://www.ncbi.nlm.nih.gov/m/pubmed/28167927/

Bivalent HPV vaccine safety depending on subtypes of juvenile idiopathic arthritis.

#Arthritis #Gardasil #Gastrointestinal #HPV #Autoimmunity #HLA
#Vaccine #MedScienceResearch

http://ard.bmj.com/content/73/12/e75.long

A case-control study of quadrivalent human papillomavirus vaccine-associated autoimmune adverse events.

“It was observed that cases with the SAAE outcomes of gastroenteritis (odds ratio (OR) = 4.6, 95% confidence interval (CI) = 1.3-18.5), arthritis (OR = 2.5, 95% CI = 1.4-4.3), systemic lupus erythematosus (OR = 5.3, 95% CI = 1.5-20.5), vasculitis (OR = 4, 95% CI = 1.01-16.4), alopecia (OR = 8.3, 95% CI = 4.5-15.9), or CNS conditions (OR = 1.8, 95% CI = 1.04-2.9) were significantly more likely than controls to have received HPV4 vaccine (median onset of SAAE symptoms from 6 to 55 days post-HPV4 vaccination).”

#Gardasil #Lupus #Arthritis #Autoimmunity #HPV #Hair #Loss
#Gastrointestinal #Alopecia #Neurological #Vaccine #MedScienceResearch

https://www.ncbi.nlm.nih.gov/m/pubmed/25535199/

A case of systemic lupus erythematosus (SLE) following Human papillomavirus (HPV) vaccination.

“A 15-year-old young woman received the Human papillomavirus (HPV) vaccines. Following the second HPV vaccination, intermittent fever, myalgia, arthritis and malar rash developed, and she was admitted to our hospital. Laboratory studies showed positive results for antinuclear antibody, anti-dsDNA antibody and anti-Sm antibody. Systemic lupus erythematosus (SLE) was diagnosed according to the Systemic Lupus International Collaborative Clinics 2012. Magnetic resonance imaging showed abnormal hyperintense areas in the fascia, and en bloc biopsy showed fasciitis. Treatment with prednisolone resulted in an amelioration of the symptoms. Reportedly, SLE developed after HPV vaccinations in some patients. Most such patients have a past or family history of autoimmune disease and presented SLE symptoms after the second vaccination. We describe herein a patient in whom SLE developed in association with HPV vaccination.”

#Gardasil #Lupus #SLE #HPV #Autoimmunity #Arthritis #Musculoskeletal #Vaccine
#MedScienceResearch

https://www.ncbi.nlm.nih.gov/m/pubmed/27212601/

The development of rheumatoid arthritis after recombinant hepatitis B vaccination.

#Rheumatoid #Arthritis
#Hepatitis B #Autoimmunity #Vaccine #MedScienceResearch

https://www.ncbi.nlm.nih.gov/m/pubmed/9733447/

Occurrence of severe destructive lyme arthritis in hamsters vaccinated with outer surface protein A and challenged with Borrelia burgdorferi.

“When the canine rOspA vaccine was combined with aluminum hydroxide, all vaccinated hamsters developed arthritis after challenge with B. burgdorferi sensu stricto. Histopathologic examination confirmed the development of severe destructive arthritis in rOspA-vaccinated hamsters challenged with B. burgdorferi sensu stricto. These findings suggest that rOspA vaccines should be modified to eliminate epitopes of OspA responsible for the induction of arthritis. Our results are important because an rOspA vaccine in aluminum hydroxide was approved by the Food and Drug Administration for use in humans.”

#Lyme #Arthritis #Aluminum #Borrelia #Vaccine #Autoimmunity #MedScienceResearch

https://www.ncbi.nlm.nih.gov/m/pubmed/10639430

A one year followup of chronic arthritis following rubella and hepatitis B vaccination based upon analysis of the Vaccine Adverse Events Reporting System (VAERS) database.

#Arthritis #Hepatitis B #Rubella #Vaccine #Autoimmunity #MedScienceResearch

https://www.ncbi.nlm.nih.gov/m/pubmed/12508767/

Postpartum rubella immunization: association with development of prolonged arthritis, neurological sequelae, and chronic rubella viremia.

#Shedding #Breastfeeding #Arthritis #Rubella #Neurological
#Vaccine #MedScienceResearch

https://www.ncbi.nlm.nih.gov/m/pubmed/4031558/

Reactive arthritis after influenza vaccination: report of a case.

“We describe a patient with reactive arthritis (ReA) induced by influenza vaccination. A healthy 79-year-old Japanese man began suffering from migrating polyarthritis 2 days after receiving influenza vaccine. He proved negative for rheumatoid factor, showing no evidence for microbial infections such as Streptoccocci, Chlamydia, or Parbovirus B19. Human leukocyte antigen (HLA) typing analysis revealed positive results for HLA-B54 (22), which is one of the cross-reactive antigens to HLA-B27. His arthritis improved with administration of nonsteroidal anti-inflammatory drugs, and recovery was attained within 6 weeks. Reactive arthritis is a rare adverse effect induced by influenza vaccination; however, it is important that it is recognized by all physicians.”

#Arthritis #HLA #Influenza #Vaccine #MedScienceResearch

https://www.ncbi.nlm.nih.gov/m/pubmed/17029078/

Severe Autoimmune Adverse Events Post Herpes Zoster Vaccine: A Case-Control Study of Adverse Events in a National Database.

“Our study showed no significantly increased risks of severe autoimmune adverse events, except arthritis and alopecia, after vaccination.”

#Hair #Loss #Arthritis #Alopecia #Shingles #Herpes #Zoster #Vaccine #MedScienceResearch

https://www.ncbi.nlm.nih.gov/m/pubmed/26151783/

Vaccinations and risk of systemic lupus erythematosus and rheumatoid arthritis: A systematic review and meta-analysis.
(2017)

“The pooled findings suggested that vaccinations significantly increased risk of SLE (RR=1.50; 95%CI 1.05-2.12, P=0.02). In addition, there was an obvious association between vaccinations and increased risk of RA (RR=1.32; 95%CI 1.09-1.60, P=0.004). Meta-analysis of studies reporting outcomes of short vaccinated time also suggested that vaccinations could significantly increase risk of SLE (RR=1.93; 95%CI 1.07-3.48, P=0.028) and RA (RR=1.48; 95%CI 1.08-2.03, P=0.015).”

#Lupus #Arthritis #Autoimmunity
#Vaccine #MedScienceResearch

https://www.ncbi.nlm.nih.gov/m/pubmed/28483543/