Aseptic meningitis after transmission of the Leningrad-Zagreb mumps vaccine from vaccinee to susceptible contact.

Vukić BT, et al. Vaccine. 2008.

No abstract available
PMID 18639602

#Recently #Vaccinated #Shedding #Mumps #Meningitis
#Vaccine #MedScienceResearch

Aseptic meningitis after vaccination against measles and mumps.

#Meningitis #Mumps #Vaccine #Failure #MedScienceResearch

Aseptic meningitis as a complication of mumps vaccination.

#MMR #Mumps #Meningitis #Vaccine #MedScienceResearch

🛑 Challenges in Interpretation of Diagnostic Test Results in a Mumps Outbreak in a Highly Vaccinated Population. 2017

“This is the first published report of an outbreak of mumps in Ontario in which all confirmed cases had been vaccinated against the disease.”

#Vaccine #Failure #Mumps #MMR

Deep sequencing reveals persistence of cell-associated mumps vaccine virus in chronic encephalitis.

“Notwithstanding this, we describe here devastating neurological complications associated with the detection of live-attenuated mumps virus Jeryl Lynn (MuV(JL5)) in the brain of a child who had undergone successful allogeneic transplantation for severe combined immunodeficiency (SCID). This is the first confirmed report of MuV(JL5) associated with chronic encephalitis and highlights the need to exclude immunodeficient individuals from immunisation with live-attenuated vaccines.”

#MMR #Mumps #Vaccine #Failure #Encephalitis #Neurological

Effect of age on the incidence of aseptic meningitis following immunization with monovalent mumps vaccine.

“A total of 10 aseptic meningitis, 551 salivary gland swelling, 844 fevers, 669 vomiting, 757 headaches, and 29 seizure cases were identified.”

#Meningitis #Mumps #Seizures #Vaccine #MedScienceResearch

Epidemic of complicated mumps in previously vaccinated young adults in the South-West of France. 2014.

“Five cases of meningitis, 1 of orchitis, and 1 of unilateral hearing impairment were identified. Each of the 7 patients had been previously vaccinated with MMR, 4 had received 2 doses of this vaccine.”

“Outbreaks of complicated mumps may still occur despite a broad coverage of MMR vaccination.”

#Mumps #Vaccine #Failure #MMR
#Meningitis #Hearing #Loss

Evidence of pestivirus RNA in human virus vaccines.

“We examined live virus vaccines against measles, mumps, and rubella for the presence of pestivirus RNA or of pestiviruses by reverse transcription PCR. Pestivirus RNA was detected in two measles-mumps-rubella combined vaccines and in two monovalent vaccines against mumps and rubella.”

#Contamination #MMR #Vaccine #Pestivirus #Mumps #Rubella #MedScienceResearch

Horizontal transmission of the Leningrad-3 live attenuated mumps vaccine virus.

“The L-3 mumps vaccine virus can be shed and transmitted horizontally, even to subjects previously vaccinated with the same virus.”

#Shedding #Mumps #Vaccine #MedScienceResearch

Horizontal transmission of the Leningrad-Zagreb mumps vaccine strain: a report of six symptomatic cases of parotitis and one case of meningitis.

“Here we report horizontal symptomatic transmission of the Leningrad-Zagreb (L-Zagreb) mumps vaccine virus. Children who were the source of transmission had been vaccinated with the MMR vaccine (Serum Institute of India) contained L-Zagreb mumps virus. This is the first report of horizontal symptomatic transmission of this vaccine. The etiology of all seven contact cases was confirmed by epidemiological linking, serology and by F, SH, NP and HN mumps virus genes sequencing.”

#Shedding #Mumps #Meningitis
#Vaccine #Failure #MMR

Horizontal transmission of the Leningrad-Zagreb mumps vaccine strain: a report of three cases.

No abstract available
PMID 18329761

#Shedding #Mumps #MMR #Vaccine #MedScienceResearch

Low vaccine efficacy of mumps component among MMR vaccine recipients in Chennai, India

“These facts inevitably state that MMR vaccine failed to offer protection in vaccinated individuals against mumps infection.”

#Mumps #MMR #Failure #Vaccine #MedScienceResearch

Molecular Analysis of Early Postvaccine Mumps-like Disease in Italian Military Recruits

“To the Editor: Italian military recruits have received mandatory mumps vaccination by Urabe Am9 strain since 1998. A previous study1 found that, in 1999, 37 episodes of mumps-like disease were found in recipients of the vaccine, and that 35 of these occurred within 1 month of immunization. To assess whether these cases were due to some expected residual virulence of the live attenuated Urabe Am9 mumps strain, we analyzed saliva samples from recruits who developed mumps-like disease within 1 month of vaccination.”

#Mumps #Vaccine

Mumps and ovarian cancer: modern interpretation of an historic association

#Mumps #Ovarian #Cancer #Vaccine #MedScienceResearch

[Mumps epidemic in vaccinated children in West Switzerland].

#Mumps #Vaccine #Failure #MMR #MedScienceResearch

Mumps vaccine associated orchitis: Evidence supporting a potential immune-mediated mechanism.

“We report 3 cases of orchitis following vaccination with mumps-measles-rubella (MMR) vaccine, two with an onset within 3 days following vaccination. Orchitis is a common complication of mumps infection, particularly in post-pubertal males, and is also recognized as a very rare complication of mumps vaccination. These cases, discussed together with a comprehensive review of the existing literature regarding post-vaccine orchitis, highlight uncertainty regarding the pathogenesis of post-vaccine orchitis.”

#MMR #Mumps #Immune #Vaccine #MedScienceResearch

🛑 [Mumps vaccine virus transmission].

“In this work we report the mumps vaccine virus shedding based on the laboratory confirmed cases of the mumps virus (MuV) infection. The likely epidemiological sources of the transmitted mumps virus were children who were recently vaccinated with the mumps vaccine containing Leningrad-Zagreb or Leningrad-3 MuV. The etiology of the described cases of the horizontal transmission of both mumps vaccine viruses was confirmed by PCR with the sequential restriction analysis.”

#Mumps #Vaccine #Failure #Shedding #MedScienceResearch

Outbreak of aseptic meningitis associated with mass vaccination with a urabe-containing measles-mumps-rubella vaccine: implications for immunization programs.

#Meningitis #MMR #Measles #Mumps #Rubella #Vaccine #Failure #MedScienceResearch

A prefecture-wide survey of mumps meningitis associated with measles, mumps and rubella vaccine.

“A survey of untoward reactions, especially central nervous system reactions, after the administration of a newly introduced measles, mumps and rubella (MMR) vaccine in Gunma Prefecture, Japan, was initiated soon after 4 patients were hospitalized for aseptic meningitis. Thirty-five, 6 and 2 children developed meningitis, convulsive disorders and parotitis, respectively, within 2 months after MMR vaccination during the 8-month period extending from April to November, 1989. The time lag between MMR vaccination and meningitis ranged from 14 to 28 days in the 35 cases of meningitis. Mumps virus, isolated from the cerebrospinal fluid in 13 patients with aseptic meningitis, was characterized by determination of the nucleotide sequences of the P gene as mumps vaccine strain. The incidence of aseptic meningitis with positive mumps vaccine virus was estimated to be 0.11% (0.3% as a whole) during the 8 months from April to November and increased to 0.3% (0.7% as a whole) in September and October. We conclude that the incidence of aseptic meningitis after MMR vaccination seems to be higher than that reported previously.”

#Mumps #Meningitis #Failure #MMR #Vaccine #MedScienceResearch

🛑 Transmission of mumps virus from mumps-vaccinated individuals to close contacts.

“During a recent mumps epidemic in the Netherlands caused by a genotype D mumps virus strain, we investigated the potential of vaccinated people to spread mumps disease to close contacts. We compared mumps viral titers of oral fluid specimens obtained by quantitative PCR from vaccinated (n=60) and unvaccinated (n=111) mumps patients. We also investigated the occurrence of mumps infection among the household contacts of vaccinated mumps patients. We found that viral titers are higher for unvaccinated patients than for vaccinated patients during the 1st 3 days after onset of disease. While no symptomatic cases were reported among the household contacts (n=164) of vaccinated mumps patients (n=36), there were cases with serological evidence of asymptomatic infection among vaccinated household contacts (9 of 66 vaccinated siblings). For two of these siblings, the vaccinated index patient was the most probable source of infection. We conclude that, in this particular outbreak, the risk of a close contact becoming infected by vaccinated patients was small, but present.
Copyright © 2011 Elsevier Ltd. All rights reserved.”

#Shedding #Mumps #Vaccine

Transmission of the L-Zagreb mumps vaccine virus, Croatia, 2005-2008.

“We report on three cases of symptomatic transmission of the L-Zagreb mumps vaccine virus from three vaccinated children to five adult contacts. The five contact cases were parents of the vaccinated children and presented with parotitis and in one case also with aseptic meningitis. The etiology of the contacts’ illness was determined by viral culture, genomic sequencing, serology and epidemiological linking. Two of the vaccinated children developed vaccine associated parotitis as an adverse event three weeks following immunization.”

#Shedding #Mumps #Meningitis
#Vaccine #Failure #MMR

Transmission of Urabe mumps vaccine between siblings.

No abstract available
PMID 8101611

#Shedding #Mumps #Vaccine #MedScienceResearch

Two successive outbreaks of mumps in Nova Scotia among vaccinated adolescents and young adults.

#Mumps #MMR #Vaccine #Failure #MedScienceResearch

Vaccines for measles, mumps and rubella in children.

“The design and reporting of safety outcomes in MMR vaccine studies, both pre- and post-marketing, are largely inadequate. The evidence of adverse events following immunisation with the MMR vaccine cannot be separated from its role in preventing the target diseases.”

#MMR #Measles #Mumps #Rubella #Febrile #Seizures #Vaccine #MedScienceResearch

Vaccine-related mumps infections in Thailand and the identification of a novel mutation in the mumps fusion protein.

#Mumps #Vaccine #Failure #MedScienceResearch

🛑 [Vaccines, biotechnology and their connection with induced abortion].

“Diploid cells (WI-38, MRC-5) vaccines have their origin in induced abortions. Among these vaccines we fi nd the following: rubella, measles, mumps, rabies, polio, smallpox, hepatitis A, chickenpox, and herpes zoster. Nowadays, other abortion tainted vaccines cultivated on transformed cells (293, PER.C6) are in the pipeline: flu, Respiratory Syncytial and parainfluenza viruses, HIV, West Nile virus, Ebola, Marburg and Lassa, hepatitis B and C, foot and mouth disease, Japanese encephalitis, dengue, tuberculosis, anthrax, plague, tetanus and malaria. The same method is used for the production of monoclonal antibodies and other proteins, gene therapy and genomics. Technology enables us to develop the aforementioned products without resorting to induced abortion. Full disclosure of the cell origin in the labelling of vaccines and other products must be supported. There are vaccines from non-objectionable sources which should be made available to the public. When no alternative vaccines exist, ethical research must be promoted. Non-objectionable sources in the production of monoclonal antibodies, gene therapy and genomics must be encouraged. It is not be consistent to abstain from products originated in embryonic stem cells and at the same time approve of products obtained from induced abortions. It is of paramount importance to avoid that induced abortion technology seeps into every field of Medicine.”

#Abortion #Aborted #Fetal #Cells #MMR #Rubella #Measles #Mumps #Rabies #Polio #Smallpox #Hepatitis A #Chickenpox #Herpes #Zoster #Shingles
#Vaccine #MedScienceResearch