Seizures

Case report: probable transmission of vaccine strain of yellow fever virus to an infant via breast milk.

#Breastfeeding #Seizures #Shedding #Yellow #Fever #Vaccine #MedScienceResearch

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3050973/

🛑 [Complications of pertussis immunization (author transl)].

“16 cases of neurological disease and/or death shortly after pertussis immunization are reported. Eight patients had convulsions, six with ensuing permanent defects. Severe polymyositis was observed in one case. Five infants died 12 h to 4 days after vaccination: two after acute encephalopathy and three in the form of a sudden unexpected death (SID). In two fatal cases the morphological changes in the brain corresponded to those of pertussis encephalopathy: neuronal degeneration in various parts of the cortex, especially in the region of the ammons horn, and in the cerebellum. There were no signs of inflammation. Three cases underwent forensic autopsy and death was attributed to bronchopulmonary infection. Complete neuropathological work-up was only done in one case, in which the brain was normal. The critique of episodical reports and the demand for prospective studies is appreciated. Knowledge of all possible forms of complications, however, is indispensable for future investigations. Polymyositis and SID have so far not been listed as abnormal reactions to immunization. The majority of our cases became known accidentally from hospital sheets or from discussions with collegues. For a detection of all possible cases a greater awareness of doctors for the problem of pertussis immunization appears necessary. Only another 23 cases have been reported to the health authorities of the state of Lower Saxony during the last 6 to 7 years. Of those, nine were either harmless reactions or diseases probably unrelated to vaccination. Two were cases of SID, 12 and 72 h after vaccination. It is concluded that only a minor proportion of possible complications is presently reported to the health authorities.”

#Sudden #Infant #Death #Syndrome #SIDS #Pertussis #Neurological #Seizures #Encephalopathy
#Musculoskeletal
#Respiratory #Vaccine
#MedScienceResearch

https://www.ncbi.nlm.nih.gov/m/pubmed/18670/?

[Demyelinating disease and vaccination of the human papillomavirus].

“CASE REPORTS: We describe the cases of four young women that developed demyelinating disease after the vaccination of the HPV, with a rank of time between the administration of the dose and the development of the clinical of seven days to a month, with similar symptoms with the successive doses. We have described six episodes coinciding after the vaccination.

CONCLUSIONS: Have been described seizures, autoimmune disorders such as Guillain-Barre syndrome, transverse myelitis, or motor neuron disease, probably adverse effects following immunization by HPV vaccine. So we suggest that vaccine may trigger an immunological mechanism leading to demyelinating events, perhaps in predisposed young.”

#Gardasil #Neurological #Seizures
#Autoimmunity #HPV
#Guillain #Barre
#Transverse #Myelitis
#Immune #Vaccine
#MedScienceResearch

https://www.ncbi.nlm.nih.gov/m/pubmed/21425100/

Dravet syndrome with SCN1B gene mutation: A rare entity. (2017)

“Early infantile epileptic encephalopathy has a grave outcome. Dravet syndrome (DS), characterized by early onset, refractory seizures, and intellectual deficit is one of the variants of the condition. SCN1B gene mutation is one of the lesser known variants of DS. Increased awareness of genetic analysis has increased the early diagnosis of DS for an early prognostication as well as genetic counselling of parents. We present the case of a 7-month old male child who started having recurrent febrile, and thereafter, afebrile seizures, following administration of a vaccination at 3 months. He developed global developmental delay, and is presently on multiple anticonvulsants. Genetic analysis was suggestive of SCN1B gene mutation associated with DS.”

#Dravet #Syndrome #Seizures #Vaccine #MedScienceResearch

https://www.ncbi.nlm.nih.gov/m/pubmed/28681755/

Effect of age on the incidence of aseptic meningitis following immunization with monovalent mumps vaccine.

“A total of 10 aseptic meningitis, 551 salivary gland swelling, 844 fevers, 669 vomiting, 757 headaches, and 29 seizure cases were identified.”

#Meningitis #Mumps #Seizures #Vaccine #MedScienceResearch

https://www.ncbi.nlm.nih.gov/m/pubmed/26431987/

🛑 Infant meningoencephalitis caused by yellow fever vaccine virus transmitted via breastmilk.

“In 2009, the first case was confirmed of meningoencephalitis caused by the yellow fever vaccine virus transmitted via breastmilk. We describe a second case in which the vaccine virus was possibly the etiologic agent of meningoencephalitis.”

#Breastfeeding #Seizures #Shedding #Neurological
#Yellow #Fever #Vaccine #MedScienceResearch

https://www.ncbi.nlm.nih.gov/m/pubmed/21461453/

The manufacturing process should remain the focus for severe febrile reactions in children administered an Australian inactivated influenza vaccine during 2010.

#Seizures #Flu #Influenza #H1N1 #Vaccine #MedScienceResearch

https://www.ncbi.nlm.nih.gov/m/pubmed/26258888

Measles-mumps-rubella-varicella combination vaccine and the risk of febrile seizures.

#Seizures #MMRV #MMR #Neurological #Vaccine #MedScienceResearch

https://www.ncbi.nlm.nih.gov/m/pubmed/20587679/

[Neurologic manifestations following pertussis vaccination].

“Twenty cases of acute neurological complications occuring within 7 days of pertussis immunization are reported. Convulsions were present in every case and status epilepticus was observed in five infants. In only 4 cases were neurological or epileptic sequelae lacking. The clustering of neurological complications in the 24 hours following immunization is not consistent with the hypothesis of a mere temporal coincidence. However, the mechanism and incidence of post-immunization encephalopathies remains obscure and epidemiological studies are in order.”

#Seizures #Encephalopathy #Neurological #Pertussis #Vaccine
#MedScienceResearch

https://www.ncbi.nlm.nih.gov/m/pubmed/240337/

Nonfebrile Seizures after Mumps, Measles, Rubella, and Varicella-Zoster Virus Combination Vaccination with Detection of Measles Virus RNA in Serum, Throat, and Urine

#MMRV #Measles #Shedding #MedScienceResearch #Seizures

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3697452/

Predictive value of seizure ICD-9 codes for vaccine safety research.

“Review of medical records confirmed whether the visit represented a true acute seizure event. 3233 visits for seizures were identified; 1024 were randomly selected for medical record review and 859 (84%) had records available.”

#Seizures #Vaccine #MedScienceResearch

https://www.ncbi.nlm.nih.gov/m/pubmed/19616500/

Recurrent seizures after diphtheria, tetanus, and pertussis vaccine immunization. Onset less than 24 hours after vaccination.

“Twenty-two patients with recurrent seizures that started less than 24 hours after immunization with diphtheria, tetanus, and pertussis (DTP) vaccine were retrospectively studied. The initial seizure generally occurred after one of the first three DTP vaccine immunizations, and followed that immunization by less than 12 hours. Two of the 22 patients were siblings. Eight patients had additional immunizations with DTP vaccine and four had immediate worsening of their seizures. Of the 22 patients, only one was seizure free and stopped taking anticonvulsants. Three patients exhibited normal development, and 11 had severe developmental delays. Based on these observations, we reviewed current contraindications for immunization with pertussis vaccine.”

#Seizures #DTP #Neurological #Vaccine #MedScienceResearch

https://www.ncbi.nlm.nih.gov/m/pubmed/6206715/

The risk of seizures after receipt of whole-cell pertussis or measles, mumps, and rubella vaccine.

#Seizures #Vaccine #MMR #DTP
#MedScienceResearch

https://www.ncbi.nlm.nih.gov/m/pubmed/11547719/

Status epilepticus and lymphocytic pneumonitis following hepatitis B vaccination.

“The case reported refers to a patient who developed status epilepticus in the day of her third dose of hepatitis B vaccination and we review the literature on this subject. A 12 year-old girl, without a relevant previous history, taking no drugs, developed a seizure attack followed by unconsciousness, and eventually died after three days of her third dose of hepatitis B (HB) vaccination. Autopsy study revealed cerebral edema with congestion and herniation and diffuse interstitial type pneumonitis. There seem to be a straight forward time relationship between the third HB vaccine, the event of convulsion and the sudden death of the patient. We suggest that, in some cases, vaccination may be the triggering factor for autoimmune and neurological disturbances in genetically predisposed individuals and physicians should be aware of this possible association.”

#Death #Neurological #Seizures #Autoimmunity #Hepatitis B #Vaccine #MedScienceResearch

https://www.ncbi.nlm.nih.gov/m/pubmed/18549949/

Syncope and seizures following human papillomavirus vaccination: a retrospective case series.

#Gardasil #Syncope #Seizures
#HPV #Neurological #Vaccine #MedScienceResearch

https://www.ncbi.nlm.nih.gov/m/pubmed/21449862/

Transmission of yellow fever vaccine virus through breast-feeding - Brazil, 2009.

#Breastfeeding #Shedding #Seizures #Yellow #Fever #Vaccine #MedScienceResearch

https://www.ncbi.nlm.nih.gov/m/pubmed/20150888/

Use of the Australian Childhood Immunisation Register for vaccine safety data

“An increase in febrile convulsions 6-11 days post-MMR vaccination was demonstrated which equates to a vaccine-attributable risk of 1 convulsion per 6753 vaccines. This study confirms the known association between MMR vaccination and febrile convulsions and in doing so demonstrates the feasibility of using the ACIR for data linkage and vaccine safety surveillance.”

#Seizures #MMR #Vaccine #MedScienceResearch

https://www.ncbi.nlm.nih.gov/m/pubmed/20430123

Vaccines for measles, mumps and rubella in children.

“The design and reporting of safety outcomes in MMR vaccine studies, both pre- and post-marketing, are largely inadequate. The evidence of adverse events following immunisation with the MMR vaccine cannot be separated from its role in preventing the target diseases.”

#MMR #Measles #Mumps #Rubella #Febrile #Seizures #Vaccine #MedScienceResearch

https://www.ncbi.nlm.nih.gov/pubmed/22336803

Vaccine-related adverse events in Cuban children, 1999-2008.

“The DTwP vaccine exhibited the highest rate of adverse events. Common minor events were: fever (17,538), reactions at injection site (4470) and systemic side effects (2422). Rare events (by WHO definition) reported were: persistent crying (2666), hypotonic-hyporesponsive episodes (3), encephalopathy (2) and febrile seizures (112). Severe events included: anaphylaxis (2), respiratory distress (1), multiple organ failure (1), sudden death (1), vaccine-associated paralytic poliomyelitis (2), toxic shock syndrome (3), and sepsis (1). The 10 deaths and 3 cases of disability were investigated by an expert commission, which concluded that 8 of the 13 severe events were vaccination-related.”

#Death #DTP #Seizures #Encephalopathy #Polio #Neurological #Vaccine #MedScienceResearch

https://www.ncbi.nlm.nih.gov/m/pubmed/22334111/