Recently Vaccinated Shedding and Injuring Others
Also see - 150 (and counting) scientific studies on shedding
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Abortive and subclinical poliomyelitis in a family during the 1992 epidemic in The Netherlands.
“We describe a case of abortive poliomyelitis due to poliovirus type 3 (PV3) in an unvaccinated woman and a subclinical poliovirus infection in her family during an epidemic in the Netherlands. The woman excreted the epidemic strain (PV3) for 7 weeks. Her two children received oral attenuated poliovirus vaccine and were subsequently found to excrete PV1 and PV2 vaccine strains in addition to the epidemic PV3 strain. Her husband, who had neutralizing antibodies to all three poliovirus types because of previous vaccination, initially excreted no virus; subsequently, however, the vaccine strain PV1 and the epidemic strain PV3 could be cultured from his feces.”
#Recently #Vaccinated #Shedding #Polio #Vaccine #MedScienceResearch
https://www.ncbi.nlm.nih.gov/m/pubmed/7742455/
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Accidental vaccinia of the vulva.
“Vaccinia of the vulva in a 32-year-old married woman is described. The vaccination was apparently due to a heteroinoculation from her husband during sexual contact. Clinically it presented as an indurated ulcer with a few isolated umbilicated vesicles and was associated with an acute biological false-positive serological reactions.”
#Shedding #Recently #Vaccinated
#Smallpox #Genital #Sexual #Transmission #Vaccine #MedScienceResearch
https://www.ncbi.nlm.nih.gov/m/pubmed/1017236/
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🛑 Accidental vaccinia vulva vaginitis.
“A thirty year old woman in whom an uncommon complication of smallpox vaccination developed is presented herein. In this case, virus was transmitted from the recently vaccinated child to the vulva and the vagina of the incompletely immune mother. The diagnosis was confirmed by a viral culture and a direct smear.”
#Shedding #Recently #Vaccinated
#Smallpox #Genital #Transmission #Vaccine #MedScienceResearch
https://www.ncbi.nlm.nih.gov/m/pubmed/7428429/
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[Acute maternal anterior poliomyelitis in a non-endemic zone].
“The authors report the case of a 26 year old woman with acute anterior poliomyelitis contracted during the vaccination of her baby. Despite having been herself vaccinated in infancy she was not protected against the poliovirus. The clinical interest of this uncommon case is a severe paralytic state with definitive paraplegia.”
#Recently #Vaccinated #Shedding
#Polio #Paralysis #Neurological #Vaccine #MedScienceResearch
https://www.ncbi.nlm.nih.gov/m/pubmed/2561040/
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Aseptic meningitis after transmission of the Leningrad-Zagreb mumps vaccine from vaccinee to susceptible contact.
Vukić BT, et al. Vaccine. 2008.
No abstract available
PMID 18639602
#Recently #Vaccinated #Shedding #Mumps #Meningitis
#Vaccine #MedScienceResearch
https://www.ncbi.nlm.nih.gov/m/pubmed/18639602/
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🛑 Conjugal transfer vaccinia.
“Two cases of conjugal contact transfer vaccinia are described. Each patient had intimate contact after their respective partners, active-duty military personnel, received the smallpox vaccination.”
#Shedding #Recently #Vaccinated
#Smallpox #Genital #Sexual#Transmission #Vaccine #MedScienceResearch
https://www.ncbi.nlm.nih.gov/m/pubmed/15337993/
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Contact vaccinia from recently vaccinated British soldiers.
#Shedding #Recently #Vaccinated
#Smallpox #Genital #Sexual #Transmission #Vaccine #MedScienceResearch
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1505686/
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🛑 Continuing mortality and morbidity from smallpox vaccination.
“Three cases of cross-infection after smallpox vaccination are described, in two of which the outcome was fatal.”
#Recently #Vaccinated #Shedding
#Death #Smallpox #Vaccine #MedScienceResearch
https://www.ncbi.nlm.nih.gov/m/pubmed/445099/
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Eczema vaccinatum resulting from the transmission of vaccinia virus from a smallpox vaccinee: an investigation of potential fomites in the home environment.
“On March 3, 2007, a 2-year-old boy was hospitalized with eczema vaccinatum. His two siblings, one with eczema, were subsequently removed from the home. Swabs of household items obtained on March 13th were analyzed for orthopoxvirus DNA signatures with real-time PCR. Virus culture was attempted on positive specimens. Eight of 25 household samples were positive by PCR for orthopoxvirus; of these, three yielded viable vaccinia virus in culture. Both siblings were found to have serologic evidence of orthopoxvirus exposure.”
#Shedding #Eczema #Smallpox #Dermatological #Vaccine
#Recently #Vaccinated
#MedScienceResearch
https://www.ncbi.nlm.nih.gov/m/pubmed/19027813/
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[An epidemic of vulvar vaccinia caused by catheterization].
No abstract available
PMID 13144592
#Shedding #Recently #Vaccinated
#Smallpox #Genital #Transmission #Vaccine #MedScienceResearch
https://www.ncbi.nlm.nih.gov/m/pubmed/13144592/
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(Not shedding but it’s the fully vaccinated.)
🛑 Finding the ‘who’ in whooping cough: vaccinated siblings are important pertussis sources in infants 6 months of age and under.
“At its peak, siblings were the most important sources of pertussis in infants 6 months and younger, particularly fully vaccinated children aged 2 and 3 years. Waning immunity before the booster at 4 years may leave this age group susceptible to infection.”
#Fully #Vaccinated
#Pertussis #Vaccine #Failure
#Waning #Immunity
#MedScienceResearch
https://www.ncbi.nlm.nih.gov/m/pubmed/25391405/
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How Contagious Is Vaccinia?
“A report on vaccine-related deaths in the United States during the 1960s found that 12 of the 68 deaths occurred in unvaccinated persons exposed to recently vaccinated family members or friends, a finding that demonstrates the potential gravity of the problem.”
“Numerous reports have described the spread of vaccinia virus within families. The majority are in- stances of single transmission, usually from a re- cently vaccinated child to an unvaccinated younger sibling.22-25 However, two or more secondary cas- es have been reported in at least eight reports of family outbreaks published from 1931 to 198126-33 (Table 2). Many of the reports describe severe, some- times fatal eczema vaccinatum in the first family member with secondary disease and substantially milder local inoculation disease in the rest of the family.”
#Recently #Vaccinated #Shedding #Death #Smallpox #Eczema #Dermatological #Vaccine
#MedScienceResearch
http://www.nejm.org/doi/pdf/10.1056/NEJMra022500
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🛑 Imported Vaccine-Associated Paralytic Poliomyelitis — United States, 2005
“This report describes the first known occurrence of imported VAPP in an unvaccinated U.S. adult who traveled abroad, where she likely was exposed through contact with an infant recently vaccinated with OPV.”
“Upon admission to a hospital in Phoenix, the patient had bilateral areflexic lower extremity weakness and respiratory failure requiring intubation.”
“The host family’s son and daughter-in-law lived next door with two children, aged 2 months and 3 years, who visited the host family frequently. The infant received his first dose of OPV on January 19, 2005, 4 days after the woman arrived to live with the host family.”
#Recently #Vaccinated #Shedding
#Polio #Paralysis
#Neurological #Respiratory
#Vaccine #MedScienceResearch
https://www.cdc.gov/mmwr/preview/mmwrhtml/mm5504a2.htm
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Intrafamilial transmission of a Sabin 1-related poliovirus in Shizuoka Prefecture, Japan.
#Recently #Vaccinated #Shedding #Polio #Neurological #Vaccine
#MedScienceResearch
http://www0.nih.go.jp/JJID/59/277.pdf
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Isolation of recombinant type 2 vaccine-derived poliovirus (VDPV) from a Nigerian child.
“A type 2 vaccine-derived poliovirus (VDPV), differing from Sabin 2 at 2.5% (22/903) of VP1 nucleotide (nt) positions, was isolated from an incompletely immunized 21-month-old Nigerian child who developed acute flaccid paralysis in 2002.”
“The date of the initiating OPV dose, calculated from the number of synonymous substitutions in the capsid region, was estimated to be approximately 16 to 18 months before onset of paralysis, a finding inconsistent with the most recent mass OPV campaign (conducted 12 days before onset of paralysis) as being the source of infection.”
#Vaccinated #Shedding #Polio #Acute #Flaccid #Paralysis #Neurological #Vaccine #Failure #MedScienceResearch
https://www.ncbi.nlm.nih.gov/m/pubmed/17449127/
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Localized accidental vaccinia of the vulva. Report of 3 cases and a review of the world literature.
No abstract available
PMID 13955695
#Shedding #Recently #Vaccinated
#Smallpox #Genital #Transmission #Vaccine #MedScienceResearch
https://www.ncbi.nlm.nih.gov/m/pubmed/13955695/
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Neonatal paralytic poliomyelitis. A case report.
“We report a child who became symptomatic with apnea at 18 days of age and who subsequently developed a permanent monoparesis. Serologic and cultural evidence indicated the virus as poliovirus vaccine type. Another infant who received live oral poliovirus vaccine was probably the source of the infecting virus.”
#Shedding #Polio
#Recently #Vaccinated
#Paralysis #Apnea
#Respiratory #Vaccine
#MedScienceResearch
https://www.ncbi.nlm.nih.gov/m/pubmed/3947264/
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Outbreak of poliomyelitis in Hispaniola associated with circulating type 1 vaccine-derived poliovirus.
“An outbreak of paralytic poliomyelitis occurred in the Dominican Republic (13 confirmed cases) and Haiti (8 confirmed cases, including 2 fatal cases) during 2000-2001. All but one of the patients were either unvaccinated or incompletely vaccinated children, and cases occurred in communities with very low (7 to 40%) rates of coverage with oral poliovirus vaccine (OPV). The outbreak was associated with the circulation of a derivative of the type 1 OPV strain, probably originating from a single OPV dose given in 1998-1999. The vaccine-derived poliovirus associated with the outbreak had biological properties indistinguishable from those of wild poliovirus.”
#Shedding #Death #Polio
#Recently #Vaccinated
#Vaccine #Failure #Paralysis
#MedScienceResearch
https://www.ncbi.nlm.nih.gov/m/pubmed/11896235/
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Poliomyelitis Associated With Type 2 Virus
Paralytic Disease in the Father of a Recently Immunized Child
“Paralytic poliomyelitis was diagnosed clinically in a 29-year-old man three weeks after his 2-year-old son received trivalent live oral poliovirus vaccine. Type 2 poliovirus with “vaccine-like” characteristics was isolated from the patient’s stool, and the serum showed a significant rise in neutralizing antibody against type 2 virus. There was no rise in complement fixation antibody titers. The patients illness was likely due to type 2 poliovirus contracted from his son. Physicians should inquire about the immunization status of parents before administering vaccine to children.”
#Recently #Vaccinated #Shedding #Polio #Paralysis #Vaccine
#MedScienceResearch
http://jamanetwork.com/journals/jama/article-abstract/335320
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Poliovirus Infections in Four Unvaccinated Children — Minnesota, August-October 2005
“On September 29, 2005, the Minnesota Department of Health (MDH) identified poliovirus type 1 in an unvaccinated, immunocompromised infant girl aged 7 months (the index patient) in an Amish community whose members predominantly were unvaccinated for polio. The patient has no paralysis; the source of the patient’s infection is unknown. Subsequently, poliovirus infections in three other children within the index patient’s community have been documented.”
“Partial sequencing of the virus capsid protein coding region (VP1) of the poliovirus genome at the MDH laboratory identified it as a vaccine-derived poliovirus (VDPV). VDPVs are poliovirus strains derived from one of the three Sabin poliovirus strains in oral polio vaccine (OPV) that have >1% difference in nucleotide sequence from the prototype vaccine virus.”
#Recently #Vaccinated #Shedding #Polio #Gastrointestinal #Vaccine #Failure #MedScienceResearch
https://www.cdc.gov/mmwr/preview/mmwrhtml/mm5441a6.htm
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Risk of Contact Vaccinia From Immunization Sites
“To the Editor: Dr Garde and and colleagues1stated that “The mechanism of transfer from the vaccinee to the spouse is uncertain.” They did not report, however, whether they asked about mouth-to-nipple contact from the vaccinee to the spouse. Oral shedding of virus could transmit the virus via direct mucosal contact.”
#Shedding #Recently #Vaccinated
#Smallpox #Sexual #Transmission #Vaccine #MedScienceResearch
http://jamanetwork.com/journals/jama/article-abstract/198749
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Secondary and tertiary transmission of vaccinia virus after sexual contact with a smallpox vaccinee–San Diego, California, 2012.
“On June 24, 2012, CDC notified Public Health Services, County of San Diego Health and Human Services Agency, of a suspected case of vaccinia virus infection transmitted by sexual contact. The case had been reported to CDC by an infectious disease specialist who had requested vaccinia immune globulin intravenous (VIGIV) (Cangene Corporation, Berwyn, Pennsylvania) for a patient with lesions suspicious for vaccinia. The patient reported two recent sexual contacts: one with a partner who recently had been vaccinated against smallpox and a later encounter with an unvaccinated partner. Infections resulting from secondary transmission of vaccinia virus from the smallpox vaccinee to the patient and subsequent tertiary transmission of the virus from the patient to the unvaccinated partner were confirmed by the County of San Diego Public Health Laboratory. The smallpox vaccine had been administered under the U.S. Department of Defense smallpox vaccination program. The vaccinee did not experience vaccine-associated complications; however, the secondary and tertiary patients were hospitalized and treated with VIGIV. No further transmission was known to have occurred. This report describes the epidemiology and clinical course of the secondary and tertiary cases and efforts to prevent further transmission to contacts.”
#Shedding #Recently #Vaccinated
#Smallpox #Genital #Sexual #Transmission #Vaccine #MedScienceResearch
https://www.ncbi.nlm.nih.gov/m/pubmed/23446513/
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Secondary transmission of varicella vaccine virus in a chronic care facility for children.
“A 16-year-old varicella-seronegative resident at a chronic care facility received varicella vaccine; 15 days later he developed severe varicella. Subsequently, a 13-year-old resident and a 39-year-old health care worker developed mild varicella. We demonstrate that vaccine-strain virus was transmitted to both persons, and that transmission included at least 2 variant vaccine strains.”
#Shedding #Recently #Vaccinated
#Vaccine #Failure #Varicella #Chickenpox #MedScienceResearch
https://www.ncbi.nlm.nih.gov/m/pubmed/16769402/
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Severe eczema vaccinatum in a household contact of a smallpox vaccinee.
“A 28-month-old child with refractory atopic dermatitis developed eczema vaccinatum after exposure to his father, a member of the US military who had recently received smallpox vaccine. The father had a history of inactive eczema but reportedly reacted normally to the vaccine. The child’s mother also developed contact vaccinia infection.”
#Recently #Vaccinated #Shedding
#Eczema #Smallpox #Dermatological #Vaccine #MedScienceResearch
https://www.ncbi.nlm.nih.gov/m/pubmed/18419490/
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Sibling transmission of vaccine-derived rotavirus (RotaTeq) associated with rotavirus gastroenteritis.
“Although rotavirus vaccines are known to be shed in stools, transmission of vaccine-derived virus to unvaccinated contacts resulting in symptomatic rotavirus gastroenteritis has not been reported to our knowledge. We document here the occurrence of vaccine-derived rotavirus (RotaTeq [Merck and Co, Whitehouse Station, NJ]) transmission from a vaccinated infant to an older, unvaccinated sibling, resulting in symptomatic rotavirus gastroenteritis that required emergency department care.”
#Recently #Vaccinated #Shedding
#Unvaccinated #Gastrointestinal
#Vaccine #Failure #Rotavirus #MedScienceResearch
https://www.ncbi.nlm.nih.gov/m/pubmed/20100758/
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Society for Assisted Reproductive Technology position statement on donor suitability of recipients of smallpox vaccine (vaccinia virus).
#Shedding #Recently #Vaccinated
#Transmission #Vaccine
#MedScienceResearch
https://www.ncbi.nlm.nih.gov/m/pubmed/17055849/
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[Spinal poliomyelitis due to contact with polio vaccine virus].
“Poliomyelitis with permanent paralysis of both legs developed in a 48-year-old woman previously not immunized against polio. The probable cause was the virus (probably Type II) contained in Sabin’s live virus vaccine, transmitted by contact with a grandchild who had been immunized with the oral vaccine.”
#Recently #Vaccinated #Shedding
#Polio #Paralysis #Unvaccinated #Vaccine #MedScienceResearch
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Surveillance of suspected poliomyelitis in Albania, 1980-1995: suggestion of increased risk of vaccine associated poliomyelitis.
“Poliovirus was isolated from six subjects who were defined as contact vaccine-associated cases. Characterization of isolates by both antigenic and molecular methods showed that, in all cases, the disease was associated with type 2 or 3 polioviruses of vaccine origin with retromutations known to be associated with loss of Sabin attenuated phenotype. Infection occurred despite the fact that all patients had records of previous immunization with oral polio vaccine (OPV), suggesting a failure of vaccination.”
#Recently #Vaccinated #Shedding
#Polio #Vaccine #Failure #MedScienceResearch
https://www.ncbi.nlm.nih.gov/m/pubmed/9682341
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Three cases of paralytic poliomyelitis associated with type 3 vaccine poliovirus strains in Bulgaria.
“Three cases of vaccine-associated paralytic poliomyelitis (two contacts and one recipient) occurred in the Bourgas region of Bulgaria in the spring of 2006. The first two cases, notified as acute flaccid paralysis, were 55 days old unvaccinated twin brothers, having been in contact with vaccinees. The third case concerned a 4-month-old infant who had received the first OPV dose 37 days prior to the onset of illness.”
#Recently #Vaccinated #Shedding #Polio #Acute #Flaccid #Paralysis #Neurological #Vaccine #Failure
#MedScienceResearch
https://www.ncbi.nlm.nih.gov/m/pubmed/19626606/
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Transmission of imported vaccine-derived poliovirus in an undervaccinated community in Minnesota.
“Oral poliovirus vaccine (OPV) has not been used in the United States since 2000. Type 1 vaccine-derived poliovirus (VDPV) was identified in September 2005, from an unvaccinated Amish infant hospitalized in Minnesota with severe combined immunodeficiency.”
#Vaccinated #Shedding #Polio
#Vaccine #Failure
#MedScienceResearch
https://www.ncbi.nlm.nih.gov/m/pubmed/19090774/
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Transmission of vaccinia virus, possibly through sexual contact, to a woman at high risk for adverse complications.
“Severe adverse events, including eczema vaccinatum (EV), can result after smallpox vaccination. Persons at risk for EV include those with underlying dermatologic conditions, such as atopic dermatitis. We investigated a case of vaccinia infection, possibly acquired during sexual contact with a recently vaccinated military service member, in a female Maryland resident with atopic dermatitis. The U.S. Department of Defense’s Vaccine Healthcare Centers Network (VHCN) and the Centers for Disease Control and Prevention (CDC) worked in conjunction with the patient’s physician and the Maryland Department of Health and Mental Hygiene (DHMH) to confirm the diagnosis, ensure treatment, and prevent further transmission. Specimens collected from the patient were tested at the DHMH laboratories and were positive by real-time polymerase chain reaction for nonvariola orthopoxvirus. Testing at the CDC verified the presence of vaccinia-specific DNA signatures. Continuing spread of the patient’s lesions led to the administration of vaccinia immune globulin and strict infection control measures to prevent tertiary transmission to vulnerable family members, also with atopic dermatitis. VHCN contacted the service member to reinforce vaccination site care and hygiene. This case underscores the importance of prevaccination education for those receiving the smallpox vaccine to protect contacts at risk for developing severe adverse reactions.”
#Shedding #Recently #Vaccinated
#Smallpox #Genital #Sexual #Transmission #Eczema #Dermatological #Vaccine #MedScienceResearch
https://www.ncbi.nlm.nih.gov/m/pubmed/24306023/
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Vaccine-associated contact paralytic poliomyelitis with atypical neurological presentation.
“Paralytic poliomyelitis presenting with quadriparesis, transient encephalitis and bulbar symptoms in 2 patients in close contact with recently vaccinated children with trivalent live oral polio vaccine is described. Symmetrical lower motor neuron involvement of deltoid muscles with electromyographic confirmation was found. Upper motor neuron signs, with symmetrical hyperactive deep tendon reflexes developed in the lower extremities. Poliovirus Type-2 vaccine-like strain was cultured from one patient and both patients showed significant antibody titers rises to poliovirus. Attention is drawn to the possible clinical differences between vaccine associated poliomelitis and the usual features found in wild strain poliomyelitis. It is suggested that in selected cases, non-immunized contacts be given inactivated polio-vaccine when the vaccinees are immunized with the live oral-vaccine.”
#Shedding #Recently #Vaccinated #Paralysis #Polio #Encephalitis
#Neurological #Vaccine #MedScienceResearch
https://www.ncbi.nlm.nih.gov/m/pubmed/3687370/
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🛑 Vaccine-associated paralytic poliomyelitis: a case report of domiciliary transmission.
“We herein present the case of an unvaccinated child, with a clinical picture of an acute anterior poliomyelitis associated with the live strain vaccine, whose brother received the Sabin vaccine 20 days before the onset of the symptoms. Vaccine strain of the type 3 poliovirus was isolated in fecal culture and a presented mutation in nucleotide 472 (C->U) in the 5′ non-coding region, which is strongly related to the higher strain virulence.”
#Shedding #Polio #Paralysis
#Recently #Vaccinated
#Neurological #Unvaccinated
#Vaccine #MedScienceResearch
https://www.ncbi.nlm.nih.gov/m/pubmed/10983013/
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Vaccine-associated paralytic poliomyelitis caused by contact infection.
“We encountered an adult patient with acute anterior poliomyelitis (AAP), whose monoparesis developed 28 days after his son’s immunization with oral poliovirus vaccine (OPV). Neurological and electrophysiological examinations suggested that his muscular wasting of the left lower limb was due to a lower motor neuron disorder, and magnetic resonance imaging revealed the responsible lesion in the left anterior horn at the thoracolumbar junction. His stool was found to include poliovirus type 3, mainly originating from Sabin 3 by neutrization antibody and PCR-restriction fragment length polymorphism method. This indicated that the AAP resulted from contact with his son.”
#Shedding #Polio #Paralysis
#Recently #Vaccinated
#Neurological #Vaccine #MedScienceResearch
https://www.ncbi.nlm.nih.gov/m/pubmed/16617188/
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[Vaccinia genitalis].
No abstract available
PMID 7167906
#Shedding #Recently #Vaccinated
#Smallpox #Genital #Transmission #Vaccine #MedScienceResearch
https://www.ncbi.nlm.nih.gov/m/pubmed/7167906/
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🛑 Vaccinia of the vulva. A case report.
#Shedding #Recently #Vaccinated
#Smallpox #Genital #Sexual #Transmission #Vaccine #MedScienceResearch
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1045005/
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Vaccinia virus infection after sexual contact with a military smallpox vaccinee -Washington, 2010.
“On March 1, 2010, the Washington State Department of Health (WADOH) notified Public Health – Seattle & King County (PHSKC) of a suspected case of contact transmission of vaccinia virus from sexual contact with a member of the military who had been vaccinated against smallpox. Vaccinia virus infection after sexual contact has been reported previously (1-4). Despite the patient’s exposure history and clinical presentation, the diagnosis initially was not considered by the patient’s physician, who ordered laboratory testing for several common sexually transmitted infections. The patient was seen by a second physician and referred to an infectious disease specialist, who obtained a swab sample of a genital lesion for laboratory testing for vaccinia virus. Vaccinia virus was confirmed by the Washington State Public Health Laboratory (WAPHL) and the CDC Poxvirus Laboratory. The patient resided in a household with an immunosuppressed renal transplant recipient. Appropriate contact precautions were recommended to the patient. No additional cases of contact transmission were reported. This report describes the patient’s clinical course and the associated epidemiologic investigation. Health-care providers caring for U.S. military personnel or their contacts should consider vaccinia virus infection in the differential diagnosis of clinically compatible genital lesions. Contact precautions should be emphasized to all persons who are vaccinated, as well as their contacts with unexplained lesions that might represent vaccinia infection from contact transmission.”
#Shedding #Recently #Vaccinated
#Smallpox #Genital #Sexual #Transmission #Vaccine #MedScienceResearch
https://www.ncbi.nlm.nih.gov/m/pubmed/20592687/
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[Vaccinia virus infection with eyelid and vulvar localization appearing after indirect contact with a recently vaccinated subject. Clinical and virological study].
No abstract available
PMID 4097683
#Shedding #Recently #Vaccinated
#Smallpox #Genital #Transmission #Eyes #Ophthalmological #Vaccine #MedScienceResearch
https://www.ncbi.nlm.nih.gov/m/pubmed/4097683/
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[Virus diseases of the external female genitals. 3. Innoculation vaccinia (localized accidental vaccinias, vaccinia vulvitis].
No abstract available
PMID 5518030
#Shedding #Recently #Vaccinated
#Smallpox #Genital #Transmission #Vaccine #MedScienceResearch
https://www.ncbi.nlm.nih.gov/m/pubmed/5518030/
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Vulval vaccinia.
No abstract available
PMID 4821486
#Shedding #Recently #Vaccinated
#Smallpox #Genital #Transmission #Vaccine #MedScienceResearch
https://www.ncbi.nlm.nih.gov/m/pubmed/4821486/
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Vulvar vaccinia infection after sexual contact with a military smallpox vaccinee–Alaska, 2006.
“On October 10, 2006, an otherwise healthy woman visited a public health clinic in Alaska after vaginal tears that she had first experienced 10 days before became increasingly painful. The patient reported having a new male sex partner during September 22-October 1, 2006. A viral swab specimen from a labial lesion of the woman was submitted to the Alaska State Virology Laboratory (ASVL) for viral culture. The viral isolate could not be identified initially and subsequently was sent to CDC on January 9, 2007, where the isolate was identified as a vaccine-strain vaccinia virus. After vaccinia was identified, investigators interviewed the woman more closely and learned that her new sex partner was a male U.S. military service member stationed at a local military base. Further investigation determined that the service member had been vaccinated for smallpox 3 days before beginning his relationship with the woman. This report describes the clinical evaluation of the woman and laboratory testing performed to identify the isolate. Health-care providers should be aware of the possibility of vaccinia infection in persons with clinically compatible genital lesions who have had recent contact with smallpox vaccinees.”
#Shedding #Recently #Vaccinated
#Smallpox #Genital #Sexual #Transmission #Vaccine #MedScienceResearch
https://www.ncbi.nlm.nih.gov/m/pubmed/17476203/
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Vulvar vaccinia infection after sexual contact with a smallpox vaccinee.
“The United States ceased generalized smallpox vaccination in 1972 but reinstated it in 2002 for military personnel and selected healthcare workers (first responders who may be investigating possible cases of smallpox or caring for patients in selected hospitals) after the 2001 bioterrorism attacks. Since reinstitution of the vaccine, reports of transmission of vaccinia virus through contact with military smallpox vaccinees have been published, including four cases of female genital infection. We report a subsequent case of vulvar vaccinia infection acquired during sexual contact with a military vaccinee.”
#Shedding #Recently #Vaccinated
#Smallpox #Genital #Sexual #Transmission #Vaccine #MedScienceResearch
https://www.ncbi.nlm.nih.gov/m/pubmed/19365178/
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Widespread eczema vaccinatum acquired by contacts. A report of an autopsy case
“A 4-month-old male infant predisposed to allergic dermatitis acquired wide-spread eczema vaccinatum by contacts with a recently vaccinated sibling. He died of acute purulent peritonitis following a perforation of multiple duodenal ulcers. Fluorescence immunocytochemical and electron microscopic studies on the skin lesions revealed the presence of viral antigens and numerous virus particles compatible morphologically with those of the mature form from the same batch of smallpox vaccine given to the sibling. A large number of virus particles in the developmental form were also predominantly scattered in the cytoplasm of cells at the stratum malpighii of the epidermis as well as in neutrophils and macrophages in the skin lesions. The virus isolation from the skin lesions was done by using the HeLa cells and the human embryonic lung fibroblasts. No abnormal laboratory data were noted in immunoglobulins. On the basis of atrophy of the thymus and other lymphatic tissues and an appearance of large pyroninophilic cells in association with blastoid transformation, the authors discussed a possible participation of the disturbance of cellular immunity secondary to the virus infection in the development of the disease.”
#Death #Recently #Vaccinated
#Shedding #Smallpox #Eczema #Vaccine #Dermatological
#MedScienceResearch
