DTaP
A clinical analysis of gelatin allergy and determination of its causal relationship to the previous administration of gelatin-containing acellular pertussis vaccine combined with diphtheria and tetanus toxoids.
#Gelatin #Allergy #DTaP #Vaccine #MMR #MedScienceResearch
https://www.ncbi.nlm.nih.gov/m/pubmed/9949325/
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Delay in diphtheria, pertussis, tetanus vaccination is associated with a reduced risk of childhood asthma
#DTaP #Asthma #Autoimmunity #Vaccine #MedScienceResearch
http://www.jacionline.org/article/S0091-6749(07)02379-2/fulltext
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DTaP with or after measles vaccination increased in-hospital mortality in Guinea-Bissau.
“RESULT: The case fatality was increased for children who had received DTP with or after measles vaccine compared with children who had received measles vaccine as the most recent vaccine, the ratio being 2.53 (1.37-4.67) and 1.77 (0.92-3.41) in the two periods, respectively.”
#Death #DTaP #DTP #Measles #MMR #Vaccine #MedScienceResearch
http://www.ncbi.nlm.nih.gov/pubmed/17092614
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Hypotonic and hyporesponsive episodes after diptheria-tetanus-acellular pertussis vaccination.
“Administration of the discontinued diphtheria-pertussis-tetanus vaccine was occasionally associated with a hypotonic-hyporesponsive episode in infants. The whole bacterial cell pertussis component was the likely culprit. For this reason, an acellular pertussis component was developed and incorporated into a new vaccine commonly called diptheria-tetanus-acellular pertussis (DTaP). Administration of DTaP vaccine has been followed by remarkably few hypotonic or hyporesponsive episodes. This report describes one of these unusual events.”
#Hypotonic #Hyporesponsive #DTAP #HHE #DTP #Vaccine
#MedScienceResearch
https://www.ncbi.nlm.nih.gov/m/pubmed/17901810/
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Preparation for global introduction of inactivated poliovirus vaccine: safety evidence from the US Vaccine Adverse Event Reporting System, 2000-12.
“Of the 41,792 adverse event reports submitted, 39,568 (95%) were for children younger than 7 years. 38,381 of the reports for children in this age group (97%) were for simultaneous vaccination with IPV and other vaccines (most commonly pneumococcal and acellular pertussis vaccines), whereas standalone IPV vaccines accounted for 0·5% of all reports. 34,880 reports were for non-serious events (88%), 3905 reports were for non-fatal serious events (10%), and 783 reports were death reports (2%). Injection-site erythema was the most commonly coded term for non-serious events (29%), and pyrexia for non-fatal serious events (38%). Most deaths (96%) were in children aged 12 months or younger; most (52%) had sudden infant death syndrome as the reported cause of death.”
#SIDS #Sudden #Infant #Death #Polio #Vaccine #Pneumococcal #DTaP #MedScienceResearch
https://www.ncbi.nlm.nih.gov/m/pubmed/26289956/
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🛑 Hypotonic-hyporesponsive episode in a 7-month-old infant after receipt of multiple vaccinations.
“A 7-month-old boy became difficult to arouse, was limp and had blue extremities 8 hours after immunization with intravenous poliovirus, diphtheria-tetanus toxoids-acellular pertussis, Haemophilus influenzae type b-hepatitis B virus and pneumococcal vaccines. The hypotonic-hyporesponsive episode had resolved by the time the infant was seen in an emergency department 1 hour later. The report describes hypotonic-hyporesponsive episode, encourages reporting of vaccine-associated adverse events and discusses prognosis and implications for subsequent immunization.”
#Hypotonic #Hyporesponsive #HHE #Polio #DTaP #Hib #Hepatitis B #Pneumococcal
#Vaccine #MedScienceResearch
https://www.ncbi.nlm.nih.gov/m/pubmed/16282941/
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Hypotonic-hyporesponsive episodes reported to the Vaccine Adverse Event Reporting System (VAERS), 1996-1998.
#Hypotonic #Hyporesponsive #HHE #DTP #DTaP #Hib #VAERS #Vaccine #MedScienceResearch
https://www.ncbi.nlm.nih.gov/m/pubmed/11015547
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Immune persistence after pertussis vaccination.
“An increased prevalence of pertussis in older populations has been found, mainly caused by waning immunity after vaccination.”
#Pertussis #DTP #DTaP #Vaccine #Failure #MedScienceResearch
https://www.ncbi.nlm.nih.gov/m/pubmed/28045580
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Lung pathology and immediate hypersensitivity in a mouse model after vaccination with pertussis vaccines and challenge with Bordetella pertussis.
#Lung #Respiratory #DTaP #Vaccine #MedScienceResearch
https://www.ncbi.nlm.nih.gov/m/pubmed/17224216/
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Neuropathology of vaccination in infants and children.
“AIMS: Documentation of clinical-pathological features of 37 infants/children whose parents alleged a relationship between vaccination and death or permanent central nervous system (CNS) damage, and sought compensation through the National Vaccine Injury Compensation Program.
SCOPE: Of the 5545 claims filed during the 10-year period (1990-1999), CNS tissue was available for evaluation by a pediatric neuropathologist in 37; 33 died and 4 had a biopsy or lobectomy. Most commonly implicated vaccines were DTP/DTaP, followed by MMR and IPV/OPV, but almost all of the vaccines currently given to infants/children were alleged to be responsible for the illness/death. No lesions were found in 5 of 37 (13.5%). The most frequent abnormality consisted of acute anoxic encephalopathy (14 of 37 - 37.8%), consequent to several different causes, such as positional asphyxia, cardio-respiratory arrest during status epilepticus, etc. The remaining children manifested other lesions, including inflammation (5 of 37 - 13.5%), vascular and developmental anomalies (4 each of 37 or 10.6%), cerebral edema and system degeneration (2 each of 37 or 5.4%), and one case of heavy metal exposure in a child living near an abandoned mine (2.2%).”
#Death #Neurological
#Polio #DTaP #MMR #DTP #Vaccine #VAERS #MedScienceResearch
https://www.ncbi.nlm.nih.gov/m/pubmed/21854821/
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Origins of and solutions for neonatal medication-dispensing errors.
“In 2008, there were five cases in which look-alike or sound-alike neonatal medication-dispensing errors occurred at our institution. A mix-up between neonatal and adult or pediatric products occurred in four of the five cases. Three of the five errors resulted in near misses with the potential to cause harm. The other two errors reached the patients but did not cause harm. The medication mix-ups involved adult and neonatal phytonadione injectable emulsion, sodium citrate injection and vancomycin-heparin combination injection, adult tetanus-diphtheria-acellular pertussis and infant diphtheria-tetanus-acellular pertussis (DTaP) vaccines, Haemophilus B and DTaP vaccines, and cisatracurium and vecuronium.”
#Error #Tdap #Hib #DTaP
#Vitamin K #Vaccine
#MedScienceResearch
https://www.ncbi.nlm.nih.gov/m/pubmed/20044369/
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Recurrence of cardiorespiratory events following repeat DTaP-based combined immunization in very low birth weight premature infants.
#DTaP #Respiratory #Cardiovascular #Vaccine #Premature #Cardiorespiratory #MedScienceResearch
https://www.ncbi.nlm.nih.gov/m/pubmed/18718262/
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Rett syndrome phenotype following infantile acute encephalopathy.
“We report on a girl who, at age 2 months, developed an acute encephalopathy with destructive brain damage 12 hours after acellular pertussis vaccination.”
#DTaP #Vaccine #Encephalopathy #Neurological #Rett
#MedScienceResearch
https://www.ncbi.nlm.nih.gov/m/pubmed/12503649/
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Timing of routine infant vaccinations and risk of food allergy and eczema at one year of age.
“…however, children with delayed DTaP had less eczema and less use of eczema medication. Timing of routine infant immunizations may affect susceptibility to allergic disease.”
#Eczema #DTaP #Autoimmunity #Vaccine #MedScienceResearch
https://www.ncbi.nlm.nih.gov/m/pubmed/26707796/
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A two-phased population epidemiological study of the safety of thimerosal-containing vaccines: a follow-up analysis.
“Phase one showed significantly increased risks for autism, speech disorders, mental retardation, personality disorders, and thinking abnormalities reported to VAERS following thimerosal-containing DTaP vaccines in comparison to thimerosal-free DTaP vaccines. Phase two showed significant associations between cumulative exposures to thimerosal and the following types of NDs: unspecified developmental delay, tics, attention deficit disorder (ADD), language delay, speech delay, and neurodevelopmental delays in general.”
#Autism #ADD #Tics #Delay #VAERS #Thimerosal #Mercury #Vaccine #DTaP #Psychiatric #Neurodevelopmental #MedScienceResearch
https://www.ncbi.nlm.nih.gov/m/pubmed/15795695
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🛑 Unexpectedly limited durability of immunity following acellular pertussis vaccination in preadolescents in a North American outbreak.
“CONCLUSIONS: Our data suggests that the current schedule of acellular pertussis vaccine doses is insufficient to prevent outbreaks of pertussis.”
#DTaP #Pertussis #Vaccine #Failure #MedScienceResearch
https://www.ncbi.nlm.nih.gov/m/pubmed/22423127/
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Why Do Pertussis Vaccines Fail?
#DTaP #DTP #Vaccine #Failure #Pertussis #MedScienceResearch
http://pediatrics.aappublications.org/content/129/5/968.extract
