Immune System

Application of the immunological disease continuum to study autoimmune and other inflammatory events after vaccination.

#Autoimmunity #Molecular #Mimicry #Immune #Vaccine #MedScienceResearch

https://www.ncbi.nlm.nih.gov/m/pubmed/21036134

Can influenza H1N1 vaccination lead to the membranous glomerulonephritis?

#Kidney #H1N1 #Influenza #Flu #Immune #Vaccine #MedScienceResearch

https://www.ncbi.nlm.nih.gov/m/pubmed/22771654/

A case of Evans’ syndrome following influenza vaccine.

“CASE REPORT: A 50-year-old man with no prior medical history developed Evans’ syndrome 4 days after receiving influenza immunization. The patient improved following treatment with oral prednisone and intravenous immunoglobulin.

CONCLUSION: Influenza vaccine is one of the most commonly used vaccines worldwide, with millions of people being vaccinated annually. Despite its wide use, only sparse information has been published concerning any hematological effects of this vaccine. The rarity of such effects supports the safety of using this vaccine.”

#Anemia #Immune #Thrombocytopenia
#Autoimmunity #Flu #Influenza #Vaccine #MedScienceResearch

https://www.ncbi.nlm.nih.gov/m/pubmed/22796025/

The common immunogenic etiology of chronic fatigue syndrome: from infections to vaccines via adjuvants to the ASIA syndrome.

#Autoimmunity #Immune #ASIA #Chronic #Fatigue #Syndrome
#Vaccine #MedScienceResearch

http://www.ncbi.nlm.nih.gov/m/pubmed/22054760/

A comprehensive review of mercury provoked autism

#Autism #Mercury #Neurological #Sensory #Immune #Vaccine #MedScienceResearch

https://www.ncbi.nlm.nih.gov/m/pubmed/19106436/

[Demyelinating disease and vaccination of the human papillomavirus].

“CASE REPORTS: We describe the cases of four young women that developed demyelinating disease after the vaccination of the HPV, with a rank of time between the administration of the dose and the development of the clinical of seven days to a month, with similar symptoms with the successive doses. We have described six episodes coinciding after the vaccination.

CONCLUSIONS: Have been described seizures, autoimmune disorders such as Guillain-Barre syndrome, transverse myelitis, or motor neuron disease, probably adverse effects following immunization by HPV vaccine. So we suggest that vaccine may trigger an immunological mechanism leading to demyelinating events, perhaps in predisposed young.”

#Gardasil #Neurological #Seizures
#Autoimmunity #HPV
#Guillain #Barre
#Transverse #Myelitis
#Immune #Vaccine
#MedScienceResearch

https://www.ncbi.nlm.nih.gov/m/pubmed/21425100/

Erythema multiforme following vaccination for human papillomavirus.

#HPV #Gardasil #Vaccine #Immune #Dermatological
#MedScienceResearch

https://www.ncbi.nlm.nih.gov/m/pubmed/19887766/

Gastrointestinal immunopathology and food allergy.

“In contrast to the beneficial expressions of gastrointestinal-associated lymphoid tissue, which are seen with relevance to newer methods of delivery of vaccines directly applied to the gastrointestinal mucosal surfaces (eg, oral poliovirus, rotavirus, Salmonella typhi vaccines), the adverse consequences of a mucosal immune response gone astray are evidenced in many diseases such as FA. A classification of clinical disorders associated with FA based on classic mechanisms of immunologic injury is presented, which includes the following: (1) IgE-mediated, (2) non-IgE-mediated, and (3) mixed IgE- and non-IgE-mediated disorders. Our study of immunologic disturbance in patients with non-IgE FA revealed a pattern of increased CD4+ and decreased TH1 cell counts in peripheral blood mononuclear cells in contrast to patients with celiac disease, where a pattern of increased CD8+ and TH1 cell counts in peripheral blood mononuclear cells and increased CD8+ cell counts was seen.”

#Food #Allergies #Gastrointestinal #Polio #Rotavirus #Immune #Vaccine
#MedScienceResearch

https://www.ncbi.nlm.nih.gov/m/pubmed/15562871/

Infection, vaccination, and autoantibodies in chronic fatigue syndrome, cause or coincidence?

#Chronic #Fatigue #Syndrome
#Immune #Vaccine #MedScienceResearch

https://www.ncbi.nlm.nih.gov/m/pubmed/19758205/

Measles inclusion-body encephalitis caused by the vaccine strain of measles virus.

#Measles #MMR #MIBE #Immune #MedScienceResearch #Vaccine #Encephalitis

https://www.ncbi.nlm.nih.gov/m/pubmed/10589903/

Mumps vaccine associated orchitis: Evidence supporting a potential immune-mediated mechanism.

“We report 3 cases of orchitis following vaccination with mumps-measles-rubella (MMR) vaccine, two with an onset within 3 days following vaccination. Orchitis is a common complication of mumps infection, particularly in post-pubertal males, and is also recognized as a very rare complication of mumps vaccination. These cases, discussed together with a comprehensive review of the existing literature regarding post-vaccine orchitis, highlight uncertainty regarding the pathogenesis of post-vaccine orchitis.”

#MMR #Mumps #Immune #Vaccine #MedScienceResearch

https://www.ncbi.nlm.nih.gov/m/pubmed/20085834/

🛑 A possible central mechanism in autism spectrum disorders, part 1.

“The autism spectrum disorders (ASD) are a group of related neurodevelopmental disorders that have been increasing in incidence since the 1980s. Despite a considerable amount of data being collected from cases, a central mechanism has not been offered. A careful review of ASD cases discloses a number of events that adhere to an immunoexcitotoxic mechanism. This mechanism explains the link between excessive vaccination, use of aluminum and ethylmercury as vaccine adjuvants, food allergies, gut dysbiosis, and abnormal formation of the developing brain. It has now been shown that chronic microglial activation is present in autistic brains from age 5 years to age 44 years. A considerable amount of evidence, both experimental and clinical, indicates that repeated microglial activation can initiate priming of the microglia and that subsequent stimulation can produce an exaggerated microglial response that can be prolonged. It is also known that one phenotypic form of microglia activation can result in an outpouring of neurotoxic levels of the excitotoxins, glutamate and quinolinic acid. Studies have shown that careful control of brain glutamate levels is essential to brain pathway development and that excesses can result in arrest of neural migration, as well as dendritic and synaptic loss. It has also been shown that certain cytokines, such as TNF-alpha, can, via its receptor, interact with glutamate receptors to enhance the neurotoxic reaction. To describe this interaction I have coined the term immunoexcitotoxicity, which is described in this article.”

#Autism #Immune #Aluminum
#Mercury #Food #Allergies
#Gastrointestinal
#Neurological #Vaccine #MedScienceResearch

http://www.ncbi.nlm.nih.gov/pubmed/19043938

Possible Triggering Effect of Influenza Vaccination on Psoriasis.

#Psoriasis #Dermatological #Influenza #Flu #Immune #Vaccine #MedScienceResearch

https://www.ncbi.nlm.nih.gov/m/pubmed/26380315

The Putative Role of Environmental Mercury in the Pathogenesis and Pathophysiology of Autism Spectrum Disorders and Subtypes. (2017)

#Autism #Mercury #Neurotoxicity #Neurodevelopmental #Mitochondria #HLA #Thimerosal #Immune #Vaccine #MedScienceResearch

https://www.ncbi.nlm.nih.gov/m/pubmed/28733900/

Smallpox and smallpox vaccination: neurological implications.

#Neurological #Smallpox #Immune
#Vaccine #MedScienceResearch

https://www.ncbi.nlm.nih.gov/m/pubmed/12707424

Subacute thyroiditis and dyserythropoesis after influenza vaccination suggesting immune dysregulation.

#Thyroid #Immune #Influenza #Flu #Vaccine #MedScienceResearch

https://www.ncbi.nlm.nih.gov/m/pubmed/22111471/

Surveillance of adverse events after the first trivalent inactivated influenza vaccine produced in mammalian cell culture (Flucelvax(®)) reported to the Vaccine Adverse Event Reporting System (VAERS), United States, 2013-2015.

“Among 309 reports with an AE documented, 19 (6.1%) were serious and the most common categories were 152 (49.2%) general disorders and administration site conditions (mostly injection site and systemic reactions) and 73 (23.6%) immune system disorders with two reports of anaphylaxis. Four reports of GBS were submitted. Disproportional reporting was identified for ‘drug administered to patient of inappropriate age.'”

#Influenza #Flu #Error #Immune #Guillain #Barre #Anaphylaxis #Vaccine #MedScienceResearch

https://www.ncbi.nlm.nih.gov/m/pubmed/26518405

Systemic Immune Response to Vaccination on FDG-PET/CT.

#Flu #Influenza #Spleen #Immune #MedScienceResearch #Vaccine

https://www.ncbi.nlm.nih.gov/m/pubmed/27994693/

Transverse myelitis and vaccines: a multi-analysis.

“We have disclosed 37 reported cases of transverse myelitis associated with different vaccines including those against hepatitis B virus, measles-mumps-rubella, diphtheria-tetanus-pertussis and others, given to infants, children and adults.”

#Transverse #Myelitis #Autoimmunity #Neurological #Immune #Hepatitis B #MMR #DTP #Vaccine #MedScienceResearch

https://www.ncbi.nlm.nih.gov/m/pubmed/19880568

Vaccinations and secondary immune thrombocytopenia with antiphospholipid antibodies by human papillomavirus vaccine.

“A 13-year-old girl developed immune thrombocytopenic purpura (ITP) and concomitant positive antiphospholipid antibodies (aPL) following vaccination with a quadrivalent human papillomavirus (HPV) vaccine. During the course of a disease, she developed clinical manifestation with bleeding and she was treated with intravenous immunoglobulins. Consequently, the number of her platelets remained critically low and she was put on corticosteroids and rituximab. Since then, her platelet count remain within the normal range, but her aPL are still present.
Published by Elsevier Inc.”

#Gardasil #HPV #Immune #Thrombocytopenia #Antiphospholipid #Vaccine #MedScienceResearch

https://www.ncbi.nlm.nih.gov/m/pubmed/27312165/

Vaccine-associated immune-mediated hemolytic anemia in the dog.

#IMHA #Animals #Dogs #Distemper #Immune #Anemia #Parvo #Vaccine #MedScienceResearch

https://www.ncbi.nlm.nih.gov/m/pubmed/8884713/